MadeMed review

What it is

MadeMed is an online clinic selling weight-loss medication, tadalafil, NAD+ and sermorelin. It shows a LegitScript Verified badge. Its medical team is led by board-certified physicians, including an internist with more than 25 years in practice. Sermorelin comes in two forms. The injection is a daily shot under the skin, sold as a 9 mg vial for 30 days. The oral form is a 1,000 mcg tablet that dissolves under the tongue. Both are compounded for each patient by licensed US compounding pharmacies and are not FDA-approved. There is no video call. Everything runs through an online form and a secure messaging portal.

How it works

You answer a five-minute online questionnaire. For the injection, you then get an IGF-1 blood test at any Labcorp or Quest location. MadeMed tells you which test to ask for after the questionnaire. Most lab visits take under 15 minutes, and results usually come back in two to three business days. If you already had the test in the last six months, you can upload results from any CLIA-certified lab, including your own doctor's. A physician reviews everything and decides within 24 hours. The tablets skip the blood test. If the doctor says no, MadeMed refunds your payment minus a $39 consultation fee. Medication ships free and discreetly each month, and the injection comes in temperature-controlled packaging. After that you can message the medical team at any time, and the doctor adjusts your dose based on how you respond. MadeMed also has a phone line.

Pricing transparency

The injection is $179 a month on a quarterly plan, billed $537 every three months. On a six-month plan it is $169 a month, billed $1,014 up front. The tablets are $109 a month quarterly, billed $327, or $99 a month on six months, billed $594. There is no one-month option. The product pages open on the six-month plan, so the first price you see is the lowest one. A $39 quarterly consultation fee is built into those prices rather than charged on top. MadeMed emails you seven days before every charge, and you can pause, skip or cancel from your dashboard in one click. A cancellation takes effect at the end of the period you already paid for, and the terms say there are no prorated refunds. If your doctor changes your dose, the price changes with it. The blood test cost is not listed. MadeMed does not take insurance, HSA or FSA cards.

Branded vs compounded

The injection is 9 mg in 3 mL, taken daily as a 30-day supply. It arrives as a powder you mix with bacteriostatic water, then inject with a small insulin-type syringe under the skin of the stomach, usually before bed. Injection supplies come in the box, and it must stay refrigerated. MadeMed sends step-by-step instructions and publishes a mixing guide on its blog. The tablet is 1,000 mcg, which MadeMed calls clinically equivalent to a 900 mcg injection. Its own blog notes that under-the-tongue forms absorb far less than injections, so ask the doctor how the dose was chosen. Published human research on sermorelin used injections. MadeMed says most people notice better sleep and energy in two to four weeks, with fuller results after eight to twelve weeks. It lists injection-site redness, headache, flushing and nausea as common side effects. It asks you to skip sermorelin with active cancer, a history of tumors, pregnancy or breastfeeding. The injection is sold in 40 states. It is not available in Alabama, Alaska, Arkansas, Hawaii, Massachusetts, Missouri, New Mexico, New York, South Carolina or Virginia.

Pros and watch-outs

The evidence behind what MadeMed prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• Is Sermorelin FDA-Approved? The Real Answer

  Sermorelin was FDA-approved once, under a different name, and that approval is gone. What is sold today is compounded — which is legal, but not the same thing as approved.

• Does sermorelin work? What the trials actually measured

  Sermorelin reliably makes your pituitary release growth hormone. Beyond that the evidence is one placebo-controlled trial in 19 adults from 1997 — lean body mass up in men only, nothing in women, and no effect on sleep in either.

How MadeMed compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Strut Health

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• bmiMD

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• Bodybuilding Health+

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More sermorelin injection sellers reviews: Joi + Blokes · MaleMD · Everlife · Precision Telemed · Amble · Heally