Joi + Blokes review
By Nora Vance · Updated October 2026
12-week supply, coaching included
Joi + Blokes sells sermorelin as an injection or a troche in 12-week supplies: $559 on subscription or $699 as a one-time purchase, with clinician care and coaching included. There is no shorter option.
Our verdict
Joi + Blokes wraps sermorelin in a fuller program than most online sellers, with coaching, messaging and lab testing on offer. The costs are a 12-week minimum, three different monthly figures across its own pages, and sales that are final once the prescription is approved.
Disclosure: Sermorelin Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.
FDA warning letter on record — public record, does not change our verdict.
At a glance
- Category
- sermorelin injections
- Format
- Injection · Oral — tablet, troche or capsule
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
What it is
Joi + Blokes is a telehealth longevity and hormone brand, with Joi for women and Blokes for men. It sells hormone therapy, peptides, weight-loss medication and at-home diagnostic lab panels. Sermorelin comes two ways, picked with a method switch on the product page. One is an injection. The other is a troche, a lozenge that dissolves in the mouth. Both cost the same, so the choice is about whether you want needles. Joi + Blokes says sermorelin is prescribed only when a clinician finds it medically necessary, not for performance enhancement.
How it works
You fill in a health history form, then a licensed partner provider reviews it, either by message or in a live consult, and decides whether a prescription fits. If it does, the medication ships to your door. If the provider decides it is not right for you, Joi + Blokes refunds you in full. After that, the program includes board-certified clinicians, one-on-one coaching, lifestyle and nutrition support, unlimited messaging and a member community. The coaches come from mixed backgrounds, including nurses, registered dietitians, personal trainers and naturopathic doctors. They help you read your results and act as your go-between with the provider. They are not doctors, though, and cannot prescribe or give specific medical advice. Joi + Blokes recommends getting lab-tested first, and its lab panels range from $149 for a 56-marker hormone panel to $699 for a 110-marker comprehensive panel. New customers are currently offered a steep code discount on labs, so check the banner before buying one. Residents of New York and New Jersey see different pricing because of state rules.
Pricing transparency
Sermorelin is sold only in 12-week supplies, and the price is the same for the injection and the troche. Subscribe and save costs $559 for each 12-week supply, with free shipping, which the page shows as $186.33 a month. A one-time purchase costs $699 for 12 weeks, shown as $233 a month. The site's product menu cards the same sermorelin at "$199/mo," which matches neither option, so go by the buy box. In practice, budget $559 or $699 at a time, not a monthly charge. Labs are a separate purchase if you choose them. Joi + Blokes does not bill insurance, but you can pay with HSA or FSA funds through Flex. Prescription sales are final, and prescription products cannot be returned. Subscriptions can be canceled, but fees already paid are not refunded.
Branded vs compounded
There is no FDA-approved sermorelin on the US market, so both forms are compounded. Joi + Blokes notes that compounded drugs are not FDA-approved and that the FDA does not verify their safety or effectiveness. The product page does not list a strength, a dose or how much medication a 12-week supply holds. The published human research on sermorelin used injections, so the troche is the less-studied route. Joi + Blokes says benefits usually build over several months, which fits its 12-week minimum. Its FAQ lays out a month-by-month timeline: energy and sleep in month one, skin and metabolism by month two, focus and libido around month three. It goes on to suggest a 5 to 10 percent drop in body fat by month six without diet or exercise. Treat that as marketing. Individual results vary widely, and the site says so too.
FDA warning letter on record
The FDA issued a warning letter naming Joi and Blokes dba Joi + Blokes — the seller this review covers.
- Letter 728283, issued June 8, 2026 — read it on fda.govFDA’s subject line: False & Misleading Claims/Misbranded (Telehealth)
We publish this because it is a matter of public record and a reader weighing this provider should have it. A warning letter is the FDA setting out alleged violations; it is not a court finding, and a company may have responded or corrected since. It does not remove Joi + Blokes from this site, and it does not change our verdict — read the letter and decide for yourself. Every letter listed here concerns advertising and labeling — how the company described its products — rather than a finding about the medication itself.
Pros and watch-outs
What we like
- Injection or troche at the same price
- Coaching, unlimited messaging and clinician care included
- Full refund if the provider says sermorelin is not right for you
- Free shipping on the subscription
- HSA and FSA accepted
Watch-outs
- No option shorter than 12 weeks
- Three different monthly figures on its own pages
- Prescription sales are final once approved
- Strength and dose not published
- Labs, if you want them, cost extra
Best for
Someone who wants sermorelin as part of a coached longevity program, with a choice of injection or troche, and who is ready to commit to 12 weeks at a time.
Who should look elsewhere
A buyer who wants to try one month first, or anyone who wants a single clear monthly price before paying.
The evidence behind what Joi + Blokes prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- Does sermorelin work? What the trials actually measured
Sermorelin reliably makes your pituitary release growth hormone. Beyond that the evidence is one placebo-controlled trial in 19 adults from 1997 — lean body mass up in men only, nothing in women, and no effect on sleep in either.
- Is Sermorelin FDA-Approved? The Real Answer
Sermorelin was FDA-approved once, under a different name, and that approval is gone. What is sold today is compounded — which is legal, but not the same thing as approved.
How Joi + Blokes compares
A few alternatives worth a look, depending on what you’re optimizing for.
Sermorelin.com
Comparing formats inside one seller
See Sermorelin.com →bmiMD
Comparing formats inside one seller
See bmiMD →- CoreAge Rx
A published price on the format you came for
See CoreAge Rx →
More sermorelin injection sellers reviews: IvologistBloom MDArc-1RxION HealthLevers HealthTonik Wellness
Reviews & prices
How we assessed this. This review reflects Sermorelin Picks’s own read of Joi + Blokes’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does Joi + Blokes charge for sermorelin?
- $559 for a 12-week supply on subscription, or $699 as a one-time purchase. The page shows these as $186.33 and $233 a month. The price is the same for injections and troches.
- Can I buy one month of sermorelin from Joi + Blokes?
- No. Joi + Blokes sells sermorelin only in 12-week supplies.
- Why does Joi + Blokes also show $199 a month for sermorelin?
- That figure appears on the site's product menu card. It does not match either option in the buy box, which charges $559 or $699 per 12 weeks. Go by the buy box.
- Can I get a refund from Joi + Blokes?
- If the provider decides sermorelin is not right for you, you get a full refund. Once a prescription is approved, sales are final and prescription products cannot be returned.
- Do I need lab work before starting sermorelin at Joi + Blokes?
- It is recommended, not stated as required. Joi + Blokes suggests lab testing first, and its panels cost $149 to $699.
- What does the Joi + Blokes health coach do?
- Coaches help you understand your lab results, answer questions about your order and pass questions to your provider. They include nurses, dietitians and trainers, but they are not doctors and cannot prescribe or diagnose.
- Is Joi + Blokes legit?
- FDA has a warning letter on record against Joi and Blokes dba Joi + Blokes, issued June 8, 2026 as letter 728283; it is linked further down this page. On this desk a warning letter discloses, it does not disqualify — it is a public record to read before you decide. Joi + Blokes is a sermorelin injection seller. What the company does not say on its own pages: which states it serves and a single monthly price you can check before an intake. Ask for those in writing before you pay.