
Onyx Weight Loss review
By Nora Vance · Updated October 2026
One plan, free consult first
Onyx Weight Loss is a North Carolina practice that sells sermorelin injections for $299 a month, one plan with no tiers, after a free consultation with one of its own providers.
Our verdict
Onyx Weight Loss is a small practice that prescribes sermorelin through scheduled telehealth visits. You get a free consultation, a named provider and one simple price. It costs more than many online sellers, and the page leaves out dose, pharmacy and billing terms.
Disclosure: Sermorelin Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.
At a glance
- Category
- sermorelin injections
- Format
- Injection
- From
- $299/mo injection
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
What it is
Onyx Weight Loss is a medical weight-loss practice based in Mooresville, North Carolina. It also offers hormone and men's health programs, and sermorelin sits among them. The practice delivers its programs by telehealth, and it lists a phone number, a fax line and a support email. It was founded by a mother and daughter, Tasha Vangile, a family nurse practitioner, and Madalyn Vangile, a registered nurse. The clinical team is nurse-led: a second nurse practitioner, several registered nurses, a clinical coordinator and a holistic nutrition coach. It describes sermorelin as a peptide that prompts the pituitary gland to release more of your own growth hormone. Only an injection is offered. There is no troche, tablet or nasal spray. What ships is a compounded prescription, not an FDA-approved finished drug.
How it works
Getting started works more like booking a clinic visit than filling in a quiz. First you book a free consultation on the booking site, choosing sermorelin as the service. Then you complete an intake and consent form at least 48 hours before the appointment. Then you meet your provider, who writes a plan around your goals. After that, Onyx promises ongoing support from the same provider. The site has a page introducing its providers, so you can see who you will talk to. Expect to meet a nurse practitioner rather than a physician, since that is who prescribes here. Visits happen over video, and patient reviews on the site mention evening appointments. Onyx also runs a nutrition coaching program, Eat To Thrive, if you want diet support alongside the injection. That suits people who want a person rather than an async review. The trade is time: the 48-hour form deadline means you cannot start the same day. The page does not say how the medication ships or how refills work.
Pricing transparency
Sermorelin costs $299 a month. That is the only figure, and it is the only plan. There is no three- or six-month rate, no first-month discount, no coupon and no separate membership fee listed. The consultation is free. A single price is easy to understand, and there is no prepay commitment to regret. The downside is that there is also no way to lower the cost by committing longer. The page does not say what the $299 includes. Ask whether it covers syringes, shipping and follow-up visits, and whether labs are extra. Also ask how billing renews and how to cancel, because no subscription or refund terms appear on the sermorelin page.
Branded vs compounded
There is no FDA-approved sermorelin on the US market, so Onyx's injection is compounded to order by a pharmacy. The page does not name that pharmacy or give a strength, so ask for both during your consultation. Onyx says early changes such as better sleep may show within weeks. It says bigger changes, such as muscle tone or fat loss, may take three to six months. Its benefits list is long, covering skin, bones, joints, mood and immunity. Treat that list as marketing rather than a promise. The published human research on sermorelin is far narrower.
Pros and watch-outs
What we like
- Free consultation before you pay anything
- One flat $299 monthly price with nothing to decode
- A real practice with a phone line and named providers
- Ongoing support from the provider who prescribes
Watch-outs
- Expensive for a single-dose monthly plan
- No discount for committing longer
- Intake form due 48 hours before your visit
- Dose, pharmacy and what the price includes are not stated
- No billing, cancellation or refund terms on the page
Best for
Someone who wants to talk to a provider before starting, values a phone number they can call, and prefers one flat price to a ladder of plans.
Who should look elsewhere
A price-first shopper, or anyone who wants to start quickly online. The plan offers no cheaper rate, and the visit has to be booked ahead with paperwork done two days early.
The evidence behind what Onyx Weight Loss prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- What Is Sermorelin? Uses, Benefits, Side Effects & FDA Status
Sermorelin does not add growth hormone to your body. It asks your pituitary to make more. How that works, what it is used for, what the one adult trial found, what it costs, and the one condition that has to be true for it to work at all.
- Sermorelin Cost: Monthly Prices From $99 to $449 (2026)
105 sermorelin sellers publish a monthly injection price, from $99 to $449. Dose, what's bundled in, and billing cadence, not quality, explain most of the gap.
How Onyx Weight Loss compares
A few alternatives worth a look, depending on what you’re optimizing for.
Rylo HealthA published price on the format you came for
See Rylo Health →- Luvo Health
A published price on the format you came for
See Luvo Health → - Embody
A published price on the format you came for
See Embody →
More sermorelin injection sellers reviews: ImmortalsMetoTelePeptideRxPepsDirectSynergenX HealthElitePhysiqMD
Reviews & prices
How we assessed this. This review reflects Sermorelin Picks’s own read of Onyx Weight Loss’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does sermorelin cost at Onyx Weight Loss?
- $299 a month as of October 2026. It is the only plan, with no longer-term discount or first-month rate. The consultation is free.
- How do I get started with Onyx Weight Loss?
- Book a free consultation online and pick sermorelin as the service. Complete the intake and consent form at least 48 hours before your appointment. Your provider then sets your plan.
- Is Onyx Weight Loss a clinic or an online service?
- Both. It is a practice in Mooresville, North Carolina, that runs its programs by telehealth. It lists a phone number and introduces its providers on the site. Sermorelin comes as an injection only, with no tablet or troche.
- Who will prescribe my sermorelin at Onyx Weight Loss?
- A nurse practitioner. Onyx's founder is a board-certified family nurse practitioner, and a second nurse practitioner sees patients too. Registered nurses and a clinical coordinator handle follow-up support between visits.
- What should I ask Onyx before paying?
- Ask what the $299 covers, which pharmacy fills the prescription, the strength of the vial, and how to cancel. None of those are on the sermorelin page.
- Is Onyx Weight Loss's sermorelin FDA-approved?
- No. No FDA-approved sermorelin is sold in the US. Onyx's injection is compounded for you by a pharmacy under a prescription.