Immortals review

What it is

Immortals is the medical arm of Bryan Johnson's longevity brand, Blueprint. It runs an online clinic with prescriptions for weight loss, longevity, skin, hair and sexual health, alongside biomarker testing. Sermorelin is sold as a nightly injection you give yourself at home. There's no tablet, troche or nasal version. You need a prescription from one of Immortals' US-licensed, board-certified physicians. Like all sermorelin sold in the US, it's compounded, and Immortals ships it from licensed US pharmacies.

How it works

Ordering takes four steps. First you complete a guided medical intake, which Immortals says takes a few minutes. A physician reviews it within 72 hours and recommends a medication only if it's appropriate. Some states require a short audio or video visit before a prescription can be approved. Approved medication ships in discreet packaging within two to five business days. Immortals puts the whole trip, from intake to your door, at three to seven days. After that, you can message your doctor any time, with video consults available, for up to 12 months. Immortals says you pay only after a doctor prescribes, and no insurance is needed. Its instructions are to inject 15 to 30 units under the skin each night, five nights a week, on an empty stomach before bed. The bedtime timing is meant to line up with the growth hormone pulse your body releases during deep sleep. Expect your doctor to suggest monitoring your biomarkers while you're on it.

Pricing transparency

There are two prices. Month to month, sermorelin is $165 a month. The "From $119/mo" figure is a three-month plan, billed quarterly and paid up front, so you'd pay about $357 at the start of each quarter. That saves $46 a month, or $138 a quarter, if you're sure you'll stay on it. Immortals charges no membership fee and says there are no hidden costs, so the medication price is what you pay. The page also says the treatment is HSA and FSA reimbursable. Over a year, month to month comes to $1,980, while four prepaid quarters come to about $1,428. Weigh that saving against the refund policy. Immortals says it cannot issue refunds or accept returns on its medicine, and all sales are final. It only invites you to get in touch if you think the pharmacy filled your prescription in error. A prepaid quarter is money you will not get back if you stop early.

Branded vs compounded

Immortals' sermorelin is compounded and prescription-only. It isn't an FDA-approved finished drug, which is true of all sermorelin on the US market. What stands out is how carefully Immortals describes it. The product card calls it "an experimental peptide protocol." The page quotes Dr. Carl Seger saying sermorelin has never been tested in a clinical trial for weight management, so that use is experimental and off-label. The dosing instructions are given in syringe units, but no concentration or vial size is published. That means you can't tell in advance how much medication a month contains. Listed side effects include injection-site reactions, antibody development, joint pain, facial flushing and nausea. Immortals says sermorelin isn't recommended during pregnancy or breastfeeding, or for anyone with a current or past cancer diagnosis.

Pros and watch-outs

The evidence behind what Immortals prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• Does sermorelin work? What the trials actually measured

  Sermorelin reliably makes your pituitary release growth hormone. Beyond that the evidence is one placebo-controlled trial in 19 adults from 1997 — lean body mass up in men only, nothing in women, and no effect on sleep in either.

• Is Sermorelin FDA-Approved? The Real Answer

  Sermorelin was FDA-approved once, under a different name, and that approval is gone. What is sold today is compounded — which is legal, but not the same thing as approved.

How Immortals compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Neo Soma Healthcare

  A published price on the format you came for

  See Neo Soma Healthcare →
• CRCoreAge Rx

  A published price on the format you came for

  See CoreAge Rx →
• MYMyDrHank

  Buyers willing to ask what it costs before ordering

  See MyDrHank →

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