One80Rx review
By Adrian Osei · Updated October 2026
From $210, priced at consult
One80Rx, a Tampa-based telehealth platform best known for GLP-1 care, lists sermorelin injections from $210 a month. The final price is set after a provider consultation.
Our verdict
One80Rx explains sermorelin well, with a clear nightly schedule, cycling and an IGF-1 recheck at month three. Its price is only a "from" figure on the catalog card, and its cancellation terms need attention before you subscribe.
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At a glance
- Category
- sermorelin injections
- Format
- Injection
- From
- From $210/mo, set at consult
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
What it is
One80Rx is a telehealth platform operated by One80Rx LLC in Tampa, Florida. Most of its catalog is GLP-1 weight loss: semaglutide, tirzepatide, microdose and oral options. A separate peptide catalog adds sermorelin, tesamorelin, an ipamorelin and CJC-1295 stack, BPC-157 and GHK-Cu. Sermorelin is sold as a compounded subcutaneous injection. One80Rx itself does not practice medicine or dispense drugs. Independent U.S. board-certified providers make the prescribing decisions, and partner compounding pharmacies prepare the medication.
How it works
You begin with a short online assessment. You must be 18 or older, and the terms say a visit may need a working video camera. A licensed provider reviews every order and prescribes only if sermorelin is clinically appropriate. Where appropriate, that review includes baseline IGF-1 labs. One80Rx describes a three-stage course. Weeks one and two start a small dose at bedtime. Weeks three to eight continue nightly dosing, often five nights on and two off. At month three the provider reassesses and may recheck IGF-1 before you continue, adjust or cycle off. Medication ships to your door in discreet packaging. Between visits you can message your care team. Support also answers by phone and email on weekdays, 9 a.m. to 5 p.m., and says it replies to contact-form messages within 24 hours. One80Rx serves only the states where it is licensed and does not list them.
Pricing transparency
The peptide catalog lists sermorelin "from $210/mo," but the sermorelin page itself shows no price and says it is available by consultation. Treat $210 as the entry point rather than a quote. Your actual charge depends on the protocol the provider sets. The terms describe a single bundled monthly price that covers the pharmacy, the medical group and platform access. Recurring orders are charged when you place them and every 30 days after. You get an email notice five to seven days before each charge. To stop, switch off auto-refill in your portal at least 48 hours before the next processing date. Because the cycle is 30 days rather than a calendar month, a year holds 13 charges. At the $210 entry price that is about $2,730 a year, $630 for three months and $1,260 for six. The terms also allow shipping or handling charges shown at checkout, so check the full total before you pay.
Branded vs compounded
There is no FDA-approved sermorelin on the US market, so One80Rx's injection is compounded. Its disclaimer says compounded medications are not FDA-approved and their safety, efficacy and quality have not been verified by the FDA. The pharmacies are described only as partner state-licensed compounding pharmacies in the United States. No dose, concentration or vial size is published, so the $210 figure cannot be compared on strength with another seller's price.
Pros and watch-outs
What we like
- Clear bedtime schedule with a five-on, two-off pattern
- Baseline and month-three IGF-1 labs described
- Cycling and reassessment built into the course
- Email notice before every recurring charge
- Care team messaging included
Watch-outs
- Price is a catalog "from" figure; final cost set at consult
- Initial orders can be canceled only within 24 hours
- No refunds once medication is dispensed
- States served not listed
- No dose, vial size or pharmacy named
Best for
Someone who wants a structured sermorelin course with lab checks and planned breaks, and who is comfortable getting a final price during the consultation.
Who should look elsewhere
Shoppers who want a fixed price before they start, or anyone who may change their mind after ordering. The price is settled at consult, and refunds are not given once medication ships.
The evidence behind what One80Rx prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- Does sermorelin work? What the trials actually measured
Sermorelin reliably makes your pituitary release growth hormone. Beyond that the evidence is one placebo-controlled trial in 19 adults from 1997 — lean body mass up in men only, nothing in women, and no effect on sleep in either.
- Is Sermorelin FDA-Approved? The Real Answer
Sermorelin was FDA-approved once, under a different name, and that approval is gone. What is sold today is compounded — which is legal, but not the same thing as approved.
- Sermorelin Dosage Chart: mcg, mL and Units vs. the Trial Dose
A mcg-to-mL-to-units chart with the math shown, the doses sermorelin trials actually used, how they compare to what sellers market, and why nobody has tested a “bodybuilding dose” in a controlled study.
How One80Rx compares
A few alternatives worth a look, depending on what you’re optimizing for.
RX BellaA published price on the format you came for
See RX Bella →- System Labs
Comparing formats inside one seller
See System Labs → - Luvo Health
A published price on the format you came for
See Luvo Health →
More sermorelin injection sellers reviews: iThriveMDREMEViKongoGarcia Weight Loss, Aesthetics & Hormone TherapyHealthSourceHarmony Wellness Clinic
Evidence & trials
How we assessed this. This review reflects Sermorelin Picks’s own read of One80Rx’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does sermorelin cost at One80Rx?
- The peptide catalog lists it from $210 a month. The sermorelin page itself shows no price and says it is available by consultation, so the provider's protocol sets your final monthly charge.
- How do I cancel a One80Rx sermorelin subscription?
- Turn off auto-refill in your patient portal at least 48 hours before the monthly processing date. A first order can be canceled within 24 hours by emailing support, if the provider network has not received it yet. After that, medication already dispensed is not refunded.
- When does One80Rx give a refund?
- Only in set cases: the wrong medication was sent, it arrived damaged, it fails safety standards, it has not shipped, or the provider declines to prescribe. Report a wrong or damaged order within 48 hours of delivery, with your order number and photos if asked. If tracking shows delivered but nothing arrived, open a claim with the carrier first.
- Does One80Rx require lab work for sermorelin?
- Where appropriate, the provider reviews baseline IGF-1 labs before prescribing and may recheck IGF-1 around month three. One80Rx does not publish what the labs cost.
- How is sermorelin dosed through One80Rx?
- As a small subcutaneous injection at bedtime. After the first two weeks, dosing often runs five nights on and two off. The provider sets the exact dose and cycle length.
- Is One80Rx the same company as RX Bella?
- No. The two sites share the same design and sermorelin page wording, but RX Bella's terms name a different operator, and the two list different prices. One80Rx is operated by One80Rx LLC in Tampa.
- What does One80Rx's monthly sermorelin price include?
- One80Rx's terms describe a single bundled subscription price. It covers the pharmacy's charge for the medication, the medical group's fee for the provider, and One80Rx's own platform fee. Labs are not mentioned as part of that bundle, so ask whether the IGF-1 tests are billed separately.
- What side effects does One80Rx list for sermorelin?
- Mostly mild reactions where you inject: redness, itching or swelling. Some people notice flushing, headache, lightheadedness or brief fluid retention. One80Rx says sermorelin is not for anyone pregnant or breastfeeding, or anyone with active cancer or a pituitary tumor.