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Sermorelin Picks

Nucific review

By Nora Vance · Updated October 2026

Supplement brand turned telehealth

Nucific, the supplement brand behind Bio-X4, now prescribes compounded sermorelin injections online from "as low as $149/month," with no membership fee and lab work and consultations folded into the price.

Our verdict

Nucific suits a shopper who wants a simple, cash-pay sermorelin injection with no membership and no separate lab or consult fees. It is especially convenient for anyone already using Nucific for GLP-1 or NAD+. The catch is how little it publishes about sermorelin itself. There is no product page, no dose and no plan breakdown behind the "as low as" figure.

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At a glance

Category
sermorelin injections
Format
Injection
From
$149/mo injection
Prescription
Required
Compounded
Yes — not FDA-approved
Labs
Included
LegitScript
Claimed by provider

Partner

RNK Health

A published price on the format you came for

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What it is

Nucific is a long-running supplement company, run by Pacific Health Supplements, LLC, best known for its Bio-X4 supplement. It now runs a telehealth side selling compounded and brand-name GLP-1s, NAD+ in several forms, B12 MIC injections and sermorelin. Its founder is Dr. Amy Lee, a physician board-certified in internal medicine, obesity medicine and clinical nutrition. She trained in internal medicine at USC and in clinical nutrition at UCLA, and serves as chief medical officer for a group of Southern California nutrition clinics. Nucific does not prescribe or compound anything itself. Clinical care comes from OpenLoop Health and affiliated networks of U.S.-licensed providers, and licensed U.S. pharmacies fill the prescriptions. Sermorelin appears as a single card in the longevity section of the homepage. It is pitched for healthy aging, restful sleep and body composition.

How it works

You start with a short online quiz that Nucific says takes about three minutes and gives a fast eligibility check. A licensed provider then reviews your answers and decides whether you qualify. If you do, approval can come the same day. Your medication ships from a licensed U.S. pharmacy in discreet packaging, with free U.S. shipping. After that you get unlimited messaging with your provider for ongoing guidance. Nucific runs a separate phone line and email for GLP-1, NAD+ and sermorelin patients, apart from its supplement support. The site does not say whether a video visit is part of the process, or which states it serves. It suggests pairing sermorelin with NAD+ or adding either to a GLP-1 plan, but you can start sermorelin on its own.

Pricing transparency

The sermorelin card reads "As low as $149/month." That is the only figure Nucific prints, and "as low as" usually means a longer plan or the starting dose. No month-to-month price or plan ladder appears next to it, so ask what the first and later months cost. The FAQ is helpful on extras. It says your treatment price includes the medication, required lab work and provider consultations, with no separate lab or consultation fees. There is no membership fee, insurance is not needed, and you can pay with HSA or FSA dollars. At the floor price, a year of sermorelin comes to at least $1,788. Nucific does not publish cancellation or refill terms beside the price. Its site-wide terms, written for the supplement shop, describe subscriptions that bill about every 30 days and cancel anytime by account, phone or email, with no early-cancellation fee. Its 90-day money-back guarantee covers products returned to its own fulfillment center. Prescriptions ship from partner pharmacies, so ask whether either rule covers sermorelin before you commit.

Branded vs compounded

Nucific's sermorelin is a compounded injection, labeled "Injectible" on its card. The site says plainly that compounded products are not FDA-approved and that the FDA does not verify their safety, effectiveness or quality. No dose, vial size, injection schedule or pharmacy name is published for sermorelin. Nucific shows a LegitScript certification badge and a BBB accreditation badge. It also has a long consumer track record as a supplement brand, which some shoppers will find reassuring. Keep in mind that the supplement business and the prescription service run through different support teams and different clinical partners.

Pros and watch-outs

What we like

  • Lab work and provider consultations included in the price
  • No membership fee; HSA and FSA accepted
  • Free, discreet U.S. shipping
  • Unlimited messaging with your provider
  • Same-day approval possible if eligible
  • LegitScript certification badge shown

Watch-outs

  • "As low as $149/month" with no plan breakdown
  • No dedicated sermorelin product page
  • No dose, vial size or schedule published
  • Pharmacy and states served not named
  • Cancellation terms not shown beside the price

Best for

Shoppers who want a straightforward cash-pay sermorelin injection with labs and consults included. It is also handy for current Nucific GLP-1 or NAD+ patients who want to add sermorelin under the same account.

Who should look elsewhere

Anyone who wants to see a dose, a named pharmacy or a full price ladder before signing up. Shoppers who prefer a clinic that specializes in peptides may also want a more focused seller.

The evidence behind what Nucific prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

  • Does sermorelin work? What the trials actually measured

    Sermorelin reliably makes your pituitary release growth hormone. Beyond that the evidence is one placebo-controlled trial in 19 adults from 1997 — lean body mass up in men only, nothing in women, and no effect on sleep in either.

  • Is Sermorelin FDA-Approved? The Real Answer

    Sermorelin was FDA-approved once, under a different name, and that approval is gone. What is sold today is compounded — which is legal, but not the same thing as approved.

How Nucific compares

A few alternatives worth a look, depending on what you’re optimizing for.

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NV
Nora Vance

Reviews & prices

How we assessed this. This review reflects Sermorelin Picks’s own read of Nucific’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does sermorelin cost at Nucific?
Nucific lists sermorelin "As low as $149/month." It does not show other plan lengths or a month-to-month rate, so confirm your actual monthly charge at checkout. Labs and provider consultations are included, and there is no membership fee.
Is Nucific's sermorelin an injection?
Yes. The sermorelin card is labeled as an injectable. Nucific does not publish the dose or schedule, which your provider sets once you are approved.
Who actually prescribes sermorelin at Nucific?
Licensed providers through OpenLoop Health and affiliated U.S. provider networks. Nucific runs the brand and the website, and licensed U.S. pharmacies fill the prescriptions.
Do I need insurance for Nucific's sermorelin?
No. Insurance is not required, and Nucific says eligible expenses can be paid with HSA or FSA funds.
Can I combine sermorelin with NAD+ or a GLP-1 at Nucific?
Nucific offers both and suggests pairing them. It says many patients combine NAD+ with sermorelin because NAD+ "may help support Sermorelin's benefits while also helping reduce fatigue." Sermorelin is sold on its own too, and your provider decides what fits.
Can I cancel Nucific's sermorelin or get a refund?
Nucific does not post separate cancellation or refund terms for its prescription service. Its general terms promise cancel-anytime subscriptions and a 90-day money-back guarantee, but they are written around supplements that ship from its own warehouse. Ask support on the sermorelin line how a prescription order is billed, paused and refunded.
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